Starting from Skype 4, we can run multiple instances of Skype. To do that, just pass /secondary argument to the skype.exe, just like this:

It will then run the 2nd instance of Skype and so on.

If you don’t like using command line tool you can make a shortcut for  it as explained in this blog post:
http://www.axelsegebrecht.com/how-to/run-multiple-instances-of-skype/

skype

In my previous blog post I wrote that the requirement to enable multi-targeting feature in Visual Studio 2010 is .NET Framework 3.5 SP1 installed in the machine. But why does it not enable the Target Framework dropdown in File -> New -> Project / Web Site dialog of Visual Studio 2010 Express edition? Is multi-targeting not supported in Visual Studio 2010 Express edition?

Visual C# 2010 Express

Visual Web Developer 2010 Express

If you’re a Visual Studio 2010 Express edition user, unfortunately you cannot take advantage of the Target Framework dropdown in the File -> New -> Project / Web Site dialog (as specified in http://msdn.microsoft.com/en-us/library/bb398197.aspx). But it doesn’t mean that multi-targeting is not supported.

By default Visual Studio 2010 Express edition will create the projects with .NET Framework 4 targeted. To change the target framework you can do it from Project Properties (Solution Explorer -> [right click your project] -> Properties)

Visual C# 2010 Express

Visual Web Developer 2010 Express

Hope this helps.

Tips & Tricks · VS2010 · VS2010-Tips